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Literature summary extracted from

  • Brady, R.O.; Gal, A.E.; Bradley, R.M.; Martensson, E.
    The metabolism of ceramide trihexosides. I. Purification and properties of an enzyme that cleaves the terminal galactose molecule of galactosylgalactosylglucosylceramide (1967), J. Biol. Chem., 242, 1021-1026.
    View publication on PubMed

General Stability

EC Number General Stability Organism
3.2.1.22 human serum albumin stabilizes Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.22 glucosylsphingosine psychosine Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.22 D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O Rattus norvegicus
-
 lactosyl-N-acylsphingosine + D-galactose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.22 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.22
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.22 brain
-
 Rattus norvegicus
-
3.2.1.22 kidney
-
 Rattus norvegicus
-
3.2.1.22 liver
-
 Rattus norvegicus
-
3.2.1.22 small intestine
-
 Rattus norvegicus
-
3.2.1.22 spleen
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.22 22
-
-
 Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
3.2.1.22 0°C, 2 weeks Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.22 D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O
-
 Rattus norvegicus lactosyl-N-acylsphingosine + D-galactose
-
 ?
3.2.1.22 additional information not: related sphingolipids Rattus norvegicus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.22 37
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.22 5
-
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.2.1.22 3.5 6 pH 6.0 about 10% of maximal activity Rattus norvegicus