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Literature summary extracted from

  • Friedman, B.; Vaddi, K.; Preston, C.; Mahon, E.; Cataldo, J.R.; McPherson, J.M.
    A comparison of the pharmacological properties of carbohydrate remodeled recombinant and placental-derived beta-glucocerebrosidase: implications for clinical efficacy in treatment of Gaucher disease (1999), Blood, 93, 2807-2816.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.2.1.45 medicine enzyme replacement therapy Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.2.1.45
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.45 glucocerebroside + H2O Homo sapiens
-
 glucose + ceramide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.45 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.2.1.45 glycoprotein contains mannose residues Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.45 of the recombinant protein Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.45 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.45 4-nitrophenyl beta-D-glucopyranoside + H2O
-
 Homo sapiens 4-nitrophenol + D-glucopyranose
-
 ?
3.2.1.45 glucocerebroside + H2O
-
 Homo sapiens glucose + ceramide
-
 ?