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Literature summary extracted from

  • Brady, R.O.; Kanfer, J.; Shapiro, D.
    The metabolism of glucocerebrosides (1965), J. Biol. Chem., 240, 39-43.
    View publication on PubMed

General Stability

EC Number General Stability Organism
3.2.1.45 dialysis, stable to Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.45 p-hydroxymercuribenzoate weak Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.45 glucocerebroside + H2O Homo sapiens
-
 glucose + ceramide
-
 ?
3.2.1.45 glucocerebroside + H2O Rattus norvegicus
-
 glucose + ceramide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.45 Homo sapiens
-
-
-
3.2.1.45 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.45
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.45 spleen
-
 Homo sapiens
-
3.2.1.45 spleen
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.45 3-O-benzoyl-N-stearylglucosphingosine + H2O not: galactocerebroside Homo sapiens D-glucose + 3-O-benzoyl-N-stearylsphingosine
-
 ?
3.2.1.45 3-O-benzoyl-N-stearylglucosphingosine + H2O not: galactocerebroside Rattus norvegicus D-glucose + 3-O-benzoyl-N-stearylsphingosine
-
 ?
3.2.1.45 glucocerebroside + H2O
-
 Homo sapiens glucose + ceramide
-
 ?
3.2.1.45 glucocerebroside + H2O
-
 Rattus norvegicus glucose + ceramide
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.45 6
-
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.2.1.45 5 8 pH 5.0: about 70% of maximum activity, pH 8.0: about 30% of maximum activity Homo sapiens