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Literature summary extracted from
- Enzyme replacement therapy in Gaucher s disease: a rapid, high-yield method for purification of glucocerebrosidase (1976), Proc. Natl. Acad. Sci. USA, 73, 4672-4674.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.2.1.45 | medicine | Gaucher disease, sphingolipoidose | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.45 | glucocerebroside + H2O | Homo sapiens | - |
glucose + ceramide | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.1.45 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.2.1.45 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.2.1.45 | placenta | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.45 | 2.5 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.45 | 4-methylumbelliferyl-beta-D-glucopyranoside + H2O | - |
Homo sapiens | methylumbelliferone + glucose | - |
? | |
| 3.2.1.45 | glucocerebroside + H2O | - |
Homo sapiens | glucose + ceramide | - |
? | |
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Release 2023.1 (January 2023)
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