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Literature summary extracted from
- Sulphatases, lysosomes and disease (1976), Aust. J. Exp. Biol. Med. Sci., 54, 111-135.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.1.6.8 | medicine | - |
Oryctolagus cuniculus |
| 3.1.6.8 | medicine | deficiency in metachromatic leukodystrophy, a sphingolipid storage disorder | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.6.8 | SO32- | competitive inhibitor | Homo sapiens |  |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.6.8 | 100000 | - |
sedimentation equilibrium ultracentrifugation | Homo sapiens |
| 3.1.6.8 | 107000 | - |
at pH 7.5 | Bos taurus |
| 3.1.6.8 | 130000 | - |
gel filtration | Homo sapiens |
| 3.1.6.8 | 140000 | - |
- |
Oryctolagus cuniculus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.6.8 | cerebroside 3-sulfate + H2O | Homo sapiens | - |
cerebroside + sulfate | - |
? | |
| 3.1.6.8 | cerebroside 3-sulfate + H2O | Bos taurus | - |
cerebroside + sulfate | - |
? | |
| 3.1.6.8 | cerebroside 3-sulfate + H2O | Oryctolagus cuniculus | - |
cerebroside + sulfate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.6.8 | Bos taurus | - |
- |
- |
| 3.1.6.8 | Homo sapiens | - |
- |
- |
| 3.1.6.8 | Oryctolagus cuniculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.6.8 | liver | - |
Homo sapiens | - |
| 3.1.6.8 | liver | - |
Oryctolagus cuniculus | - |
| 3.1.6.8 | urine | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.6.8 | cerebroside 3-sulfate + H2O | - |
Homo sapiens | cerebroside + sulfate | - |
? | |
| 3.1.6.8 | cerebroside 3-sulfate + H2O | - |
Bos taurus | cerebroside + sulfate | - |
? | |
| 3.1.6.8 | cerebroside 3-sulfate + H2O | - |
Oryctolagus cuniculus | cerebroside + sulfate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.6.8 | monomer | at pH 5.6 monomer, at pH 4.8 tetramer | Bos taurus |
| 3.1.6.8 | monomer | 1 * 140000, each monomer consists of 2 equivalent polypeptide chains | Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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