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Literature summary extracted from

  • Farooqui, A.A.; Bachhawat, B.K.
    Purification and properties of arylsulphatase A from chicken brain (1972), Biochem. J., 126, 1025-1033.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.6.8 ascorbate alone no effect, enhances the inhibition by Cu2+ Gallus gallus
3.1.6.8 CN-
-
 Gallus gallus
3.1.6.8 Cu2+ inhibition enhanced in presence of carbonyl reagents or ascorbic acid Gallus gallus
3.1.6.8 F-
-
 Gallus gallus
3.1.6.8 N-ethylmaleimide no inhibition at pH 5.5, but at pH 5.0 Gallus gallus
3.1.6.8 p-hydroxymercuribenzoate no inhibition at pH 5.5, but at pH 5.0 Gallus gallus
3.1.6.8 PO43-
-
 Gallus gallus
3.1.6.8 SO32-
-
 Gallus gallus
3.1.6.8 SO42-
-
 Gallus gallus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.6.8 lysosome
-
 Gallus gallus 5764
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.6.8 cerebroside 3-sulfate + H2O Gallus gallus
-
 cerebroside + sulfate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.8 Gallus gallus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.6.8
-
 Gallus gallus

Reaction

EC Number Reaction Comment Organism Reaction ID
3.1.6.8 a cerebroside 3-sulfate + H2O = a cerebroside + sulfate hydrolyses galactose-3-sulfate residues in a number of lipids, also hydrolyses ascorbate 2-sulfate and many phenol sulfates, enzymes catalyze in addition to reaction of EC 3.1.6.8 also arylsulfatase reaction EC 3.1.6.1 Gallus gallus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.6.8 brain
-
 Gallus gallus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.6.8 1.5
-
 nitrocatechol sulfate Gallus gallus

Storage Stability

EC Number Storage Stability Organism
3.1.6.8 0°C, 2 months Gallus gallus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.8 cerebroside 3-sulfate + H2O
-
 Gallus gallus cerebroside + sulfate
-
 ?
3.1.6.8 nitrocatechol sulfate + H2O
-
 Gallus gallus nitrocatechol + sulfate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.6.8 37
-
 assay Gallus gallus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.6.8 5 5.5 pH optimum depends on time of incubation, 5-20 min: pH 5.5, 30-90 min: pH 5.0 Gallus gallus