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Literature summary extracted from

  • Waheed, A.; Van Etten, R.L.
    Chemical characterization and substrate specificity of rabbit liver aryl sulfatase A (1980), Biochim. Biophys. Acta, 614, 92-101.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.6.8 0.06
-
 cerebroside 3-sulfate in presence of 10 mM sodium formate Oryctolagus cuniculus
3.1.6.8 0.35
-
 p-nitrocatechol sulfate
-
 Oryctolagus cuniculus
3.1.6.8 3
-
 p-nitrophenol sulfate
-
 Oryctolagus cuniculus
3.1.6.8 4
-
 4-methylumbelliferone sulfate
-
 Oryctolagus cuniculus
3.1.6.8 15.9
-
 1-naphthyl sulfate
-
 Oryctolagus cuniculus
3.1.6.8 31.8
-
 Tyrosine O-sulfate
-
 Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.6.8 lysosome
-
 Oryctolagus cuniculus 5764
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.6.8 140000
-
 zonal and frontal gel filtration Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.6.8 cerebroside 3-sulfate + H2O Oryctolagus cuniculus
-
 cerebroside + sulfate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.8 Oryctolagus cuniculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.6.8 glycoprotein liver: 4.6% carbohydrate Oryctolagus cuniculus

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.6.8
-
 Oryctolagus cuniculus

Reaction

EC Number Reaction Comment Organism Reaction ID
3.1.6.8 a cerebroside 3-sulfate + H2O = a cerebroside + sulfate hydrolyses galactose-3-sulfate residues in a number of lipids, also hydrolyses ascorbate 2-sulfate and many phenol sulfates, enzymes catalyze in addition to reaction of EC 3.1.6.8 also arylsulfatase reaction EC 3.1.6.1 Oryctolagus cuniculus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.6.8 liver
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.8 1-naphthyl sulfate + H2O
-
 Oryctolagus cuniculus 1-naphthol + sulfate
-
 ?
3.1.6.8 4-nitrophenyl sulfate + H2O
-
 Oryctolagus cuniculus 4-nitrophenol + sulfate
-
 ?
3.1.6.8 ascorbate 2-sulfate + H2O
-
 Oryctolagus cuniculus ascorbate + sulfate
-
 ?
3.1.6.8 cerebroside 3-sulfate + H2O
-
 Oryctolagus cuniculus cerebroside + sulfate
-
 ?
3.1.6.8 dehydroisoandrosterone sulfate + H2O
-
 Oryctolagus cuniculus dehydroisoandrosterone + sulfate
-
 ?
3.1.6.8 estriol 3-sulfate + H2O
-
 Oryctolagus cuniculus estriol + sulfate
-
 ?
3.1.6.8 estrone 3-sulfate + H2O
-
 Oryctolagus cuniculus estrone + sulfate
-
 ?
3.1.6.8 methylumbelliferyl sulfate + H2O
-
 Oryctolagus cuniculus methylumbelliferone + sulfate
-
 ?
3.1.6.8 nitrocatechol sulfate + H2O
-
 Oryctolagus cuniculus nitrocatechol + sulfate
-
 ?
3.1.6.8 tyrosine O-sulfate + H2O
-
 Oryctolagus cuniculus tyrosine + sulfate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.6.8 monomer 1 * 140000, each monomer consists of 2 equivalent polypeptide chains Oryctolagus cuniculus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.6.8 37
-
 assay Oryctolagus cuniculus