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Literature summary extracted from
- Human placental steroid-sulfatase. Kinetics of the in-vitro hydrolysis of dehydroepiandrosterone 3-sulfate and of 16 alpha-hydroxydehydroepiandrosterone 3-sulfate (1983), Hoppe-Seyler's Z. Physiol. Chem., 364, 187-191.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.6.2 | 16alpha-hydroxydehydroepiandrosterone | competitive to dihydroepiandrosterone | Homo sapiens |  |
| 3.1.6.2 | dehydroepiandrosterone | competitive to 16alpha-hydroxydehydroepiandrosterone | Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.6.2 | 0.003 | - |
dehydroepiandrosterone 3-sulfate | - |
Homo sapiens | |
| 3.1.6.2 | 0.008 | - |
dehydroepiandrosterone 3-sulfate | - |
Homo sapiens | |
| 3.1.6.2 | 0.02 | - |
16alpha-hydroxydehydroepiandrosterone 3-sulfate | - |
Homo sapiens | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.6.2 | steroid sulfates + H2O | Homo sapiens | also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site | steroid + sulfate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.6.2 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.6.2 | placenta | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.6.2 | 16alpha-hydroxydehydroepiandrosterone 3-sulfate + H2O | - |
Homo sapiens | 16alpha-hydroxydehydroepiandrosterone + sulfate | - |
? | |
| 3.1.6.2 | dehydroepiandrosterone 3-sulfate + H2O | - |
Homo sapiens | dehydroepiandrosterone + sulfate | - |
? | |
| 3.1.6.2 | steroid sulfates + H2O | also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site | Homo sapiens | steroid + sulfate | - |
? | |
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