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Literature summary extracted from

  • Simard, J.P.S.; Ameen, M.; Chang, P.L.
    Biochemical characterization of arylsulfatase-C isozymes in human fibroblasts (1985), Biochem. Biophys. Res. Commun., 128, 1388-1394.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.1.6.2 medicine
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.6.2 0.005
-
 esterone 3-sulfate
-
 Homo sapiens
3.1.6.2 0.217
-
 4-methylumbelliferylsulfate
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.6.2 steroid sulfates + H2O Homo sapiens also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site steroid + sulfate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.2 Homo sapiens
-
 fast form in patients with X-linked ichthyosis
-
3.1.6.2 Homo sapiens
-
 2 forms of arylsulfatase C: slow form, fast form, only slow form is associated with sterol sulfatase activity
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.6.2 skin cultured fibroblasts Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.2 4-methylumbelliferyl sulfate + H2O
-
 Homo sapiens 4-methylumbelliferone + sulfate
-
 ?
3.1.6.2 dehydroisoandrosterone 3-sulfate + H2O
-
 Homo sapiens dehydroisoandrosterone + sulfate
-
 ?
3.1.6.2 estrone sulfate + H2O
-
 Homo sapiens estrone + sulfate
-
 ?
3.1.6.2 steroid sulfates + H2O also acts on some related steryl sulfates, phenol sulfates, steroid arylsulfates and steroid alkyl sulfates catalyzed at the same site Homo sapiens steroid + sulfate
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.1.6.2 60
-
 10 min, 50% loss of activity Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.6.2 7.7
-
 fast form Homo sapiens
3.1.6.2 8
-
 slow form Homo sapiens