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Literature summary extracted from
- CMP-N-acetylneuraminic acid hydrolase, an ectoenzyme distributed unevenly over the hepatocyte surface (1977), Biochim. Biophys. Acta, 466, 187-197.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.4.40 | plasma membrane | activity in subfractions | Rattus norvegicus | 5886 | - |
| 3.1.4.40 | plasma membrane | outside of cellular membranes | Rattus norvegicus | 5886 | - |
| 3.1.4.40 | plasma membrane | sinusoidal and/or lateral surface of hepatocytes | Rattus norvegicus | 5886 | - |
| 3.1.4.40 | plasma membrane | of liver cells | Rattus norvegicus | 5886 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.40 | CMP-N-acylneuraminate + H2O | Rattus norvegicus | - |
? | - |
? |  |
| 3.1.4.40 | CMP-N-acylneuraminate + H2O | Rattus norvegicus Wistar | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.4.40 | Rattus norvegicus | - |
Wistar | - |
| 3.1.4.40 | Rattus norvegicus Wistar | - |
Wistar | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.4.40 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.40 | additional information | - |
- |
Rattus norvegicus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 3.1.4.40 | -20°C, 1 mM Tris-HCl buffer, pH 8, membrane preparations | Rattus norvegicus |
| 3.1.4.40 | 0-4°C, different sucrose concentrations, for several days, no inactivation | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.40 | CMP-N-acylneuraminate + H2O | - |
Rattus norvegicus | CMP + N-acylneuraminate | - |
? | |
| 3.1.4.40 | CMP-N-acylneuraminate + H2O | - |
Rattus norvegicus Wistar | CMP + N-acylneuraminate | - |
? | |
| 3.1.4.40 | CMP-N-acylneuraminate + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.1.4.40 | CMP-N-acylneuraminate + H2O | - |
Rattus norvegicus Wistar | ? | - |
? | |
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