EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.4 | cholic acid | - |
Actinomadura sp. | |
3.1.4.4 | ethyl ether | stimulates | Actinomadura sp. | |
3.1.4.4 | sodium deoxycholate | - |
Actinomadura sp. | |
3.1.4.4 | Triton X-100 | substrate-dependent activation | Actinomadura sp. |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.4 | Ag2+ | in the presence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Al3+ | stimulates in the absence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Cetylpyridinium chloride | - |
Actinomadura sp. | |
3.1.4.4 | cetyltrimethylammonium bromide | - |
Actinomadura sp. | |
3.1.4.4 | Fe2+ | stimulates in the absence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Fe3+ | stimulates in the absence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Hg2+ | in the presence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Mn2+ | stimulates in the absence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | SDS | - |
Actinomadura sp. | |
3.1.4.4 | Sn2+ | stimulates in the absence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Triton X-100 | substrate-dependent inhibition | Actinomadura sp. |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.4.4 | 0.7 | - |
phosphatidylcholine | in the presence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | 1.07 | - |
lysophosphatidylcholine | in the presence of Triton X-100 | Actinomadura sp. |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.4.4 | extracellular | - |
Actinomadura sp. | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.4 | Al3+ | stimulates in the absence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Ca2+ | - |
Actinomadura sp. | |
3.1.4.4 | Fe2+ | stimulates in the absence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Fe3+ | stimulates in the absence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Mn2+ | stimulates in the absence of Triton X-100 | Actinomadura sp. | |
3.1.4.4 | Sn2+ | stimulates in the absence of Triton X-100 | Actinomadura sp. |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.4.4 | 50000 | 60000 | gel filtration, SDS-PAGE | Actinomadura sp. |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.4.4 | phospholipid + alcohol | Actinomadura sp. | transphosphaditylation | phospholipid + alcohol | - |
? | |
3.1.4.4 | phospholipid + H2O | Actinomadura sp. | phosphoric ester hydrolysis | phosphatidic acid + alcohol | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.4.4 | Actinomadura sp. | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.4.4 | to homogeneity | Actinomadura sp. |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.4.4 | culture supernatant | - |
Actinomadura sp. | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.1.4.4 | 688 | - |
- |
Actinomadura sp. |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.4.4 | lysophosphatidylcholine + H2O | - |
Actinomadura sp. | monoacylglycerophosphate + choline | - |
? | |
3.1.4.4 | phosphatidylcholine + ethanolamine | - |
Actinomadura sp. | phosphatidylethanolamine + choline | - |
? | |
3.1.4.4 | phosphatidylcholine + H2O | - |
Actinomadura sp. | 1,2-diacylglycerophosphate + choline | - |
? | |
3.1.4.4 | phosphatidylethanolamine + H2O | - |
Actinomadura sp. | 1,2-diacylglycerophosphate + ethanolamine | - |
? | |
3.1.4.4 | phospholipid + alcohol | transphosphaditylation | Actinomadura sp. | phospholipid + alcohol | - |
? | |
3.1.4.4 | phospholipid + H2O | phosphoric ester hydrolysis | Actinomadura sp. | phosphatidic acid + alcohol | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.4.4 | 50 | - |
in the presence of Triton X-100 | Actinomadura sp. |
3.1.4.4 | 60 | 70 | in the absence of Triton X-100 | Actinomadura sp. |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.4.4 | 30 | - |
at pH 7.2 for 30 min | Actinomadura sp. |
3.1.4.4 | 30 | - |
irreversible loss of activity at higher temperature | Actinomadura sp. |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.4.4 | 5.5 | 7 | Triton X-100 dependent | Actinomadura sp. |
EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|---|
3.1.4.4 | 4 | 8 | 2 h at 25°C | Actinomadura sp. |