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Literature summary extracted from

  • Thomas, M.K.; Francis, S.H.; Corbin, J.D.
    Characterization of a purified bovine lung cGMP-binding cGMP phosphodiesterase (1990), J. Biol. Chem., 265, 14964-14970.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.35 3-isobutyl-1-methyl-8-methoxymethylxanthine
-
 Bos taurus
3.1.4.35 3-isobutyl-1-methylxanthine
-
 Bos taurus
3.1.4.35 Cilostamide
-
 Bos taurus
3.1.4.35 dipyridamole
-
 Bos taurus
3.1.4.35 rolipram
-
 Bos taurus
3.1.4.35 theophylline
-
 Bos taurus
3.1.4.35 zaprinast
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.4.35 0.0056
-
 3',5'-cGMP
-
 Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.4.35 178000
-
 calculated native molecular weight Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.35 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.35
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.35 lung
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.35 3',5'-cGMP + H2O
-
 Bos taurus 5'-GMP
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.4.35 dimer 2 + 93000, SDS-PAGE Bos taurus