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Literature summary extracted from

  • Matsuzawa, Y.; Hostetler, K.Y.
    Properties of phospholipase C isolated from rat liver lysosomes (1980), J. Biol. Chem., 255, 646-652.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.3 Ca2+
-
 Rattus norvegicus
3.1.4.3 Co2+
-
 Rattus norvegicus
3.1.4.3 Mg2+
-
 Rattus norvegicus
3.1.4.3 Mn2+
-
 Rattus norvegicus
3.1.4.3 sodium deoxycholate
-
 Rattus norvegicus
3.1.4.3 Zn2+
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.3 lysosome
-
 Rattus norvegicus 5764
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.3 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.3 liver
-
 Rattus norvegicus
-

Storage Stability

EC Number Storage Stability Organism
3.1.4.3 -60°C, for one year, activity only slightly decreased Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.3 1,2-dioleoylphosphatidylcholine + H2O
-
 Rattus norvegicus 1,2-dioleoylglycerol + phosphorylcholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Rattus norvegicus 1,2-diacylglycerol + phosphorylcholine
-
 ?
3.1.4.3 phosphatidylethanolamine + H2O
-
 Rattus norvegicus phosphorylethanolamine + diacylglycerol
-
 ?
3.1.4.3 phosphatidylglycerol + H2O
-
 Rattus norvegicus 1,2-diacylglycerol + sn-glycerol-3-phosphate
-
 ?
3.1.4.3 phosphatidylinositol + H2O
-
 Rattus norvegicus inositol monophosphate + diacylglycerol
-
 ?
3.1.4.3 phosphatidylserine + H2O
-
 Rattus norvegicus phosphorylserine + diacylglycerol
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.4.3 4.4
-
 substrate: 1,2-dioleoyl-3-phosphatidylcholine Rattus norvegicus