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Literature summary extracted from

  • Lee, C.W.; Lee, K.H.; Rhee, S.G.
    Characterization of phospholipase C isoenzymes in bovine retina: Purification of phospholipase C-beta 4 (1994), Methods Enzymol., 238, 227-237.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.4.3 85000
-
 PLC delta 1 and PLC delta 2 Bos taurus
3.1.4.3 100000
-
 PLC beta 1 isoform Bos taurus
3.1.4.3 130000
-
 PLC beta 4, isoforms with slightly different MW exist Bos taurus
3.1.4.3 140000
-
 PLC beta 1 isoform Bos taurus
3.1.4.3 145000
-
 PLC gamma 1 Bos taurus
3.1.4.3 150000
-
 PLC beta 1 isoform Bos taurus
3.1.4.3 152000
-
 PLC beta 3 Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.3 phosphatidylinositol-bisphosphate + H2O Bos taurus
-
 inositol 1,4,5-trisphosphate + 1,2-diacylglycerol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.3 Bos taurus
-
 cow
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.3 column chromatography, ion-exchange chromatography Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.3 retina
-
 Bos taurus
-

Storage Stability

EC Number Storage Stability Organism
3.1.4.3 -70°C Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.3 phosphatidylinositol + H2O
-
 Bos taurus inositol monophosphate + diacylglycerol
-
 ?
3.1.4.3 phosphatidylinositol-bisphosphate + H2O
-
 Bos taurus inositol 1,4,5-trisphosphate + 1,2-diacylglycerol
-
 ?