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Literature summary extracted from

  • Mukai, J.; Asai, T.; Naka, M.; Tanaka, T.
    Separation and characterization of a novel isoenzyme of cyclic nucleotide phosphodiesterase from rat cerebrum (1994), Br. J. Pharmacol., 111, 389-390.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.17 nicardipine weak inhibitor Rattus norvegicus
3.1.4.17 rolipram weak inhibitor Rattus norvegicus
3.1.4.17 SKF 94120 weak inhibitor Rattus norvegicus
3.1.4.17 zaprinast weak inhibitor Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.4.17 additional information
-
 additional information three isoenzymes Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.17 cytosol
-
 Rattus norvegicus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.17 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.17 telencephalon
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.17 3',5'-cAMP + H2O
-
 Rattus norvegicus 5'-AMP
-
 ?
3.1.4.17 3',5'-cGMP + H2O
-
 Rattus norvegicus 5'-GMP
-
 ?
3.1.4.17 nucleoside 3',5'-cyclic phosphate + H2O
-
 Rattus norvegicus nucleoside 5'-phosphate
-
 ?