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Literature summary extracted from

  • Leroy, M.J.; Degerman, E.; Taira, M.; Murata, T.; Wang, L.H.; Movsesian, M.A.; Meacci, E.; Manganiello, V.C.
    Characterization of two recombinant PDE3 (cGMP inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells (1996), Biochemistry, 35, 10194-10202.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.4.17 expression in NIH3006 murine fibroblasts and baculovirus-infected Sf9 insect cells Homo sapiens
3.1.4.17 expression in NIH3006 murine fibroblasts and Sf9 insect cells Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.17 cGMP
-
Homo sapiens
3.1.4.17 cGMP
-
Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.17 Homo sapiens
-
-
-
3.1.4.17 Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.17 3',5'-cAMP + H2O
-
Homo sapiens 5'-AMP
-
?
3.1.4.17 3',5'-cAMP + H2O
-
Rattus norvegicus 5'-AMP
-
?
3.1.4.17 nucleoside 3',5'-cyclic phosphate + H2O
-
Homo sapiens nucleoside 5'-phosphate
-
?
3.1.4.17 nucleoside 3',5'-cyclic phosphate + H2O
-
Rattus norvegicus nucleoside 5'-phosphate
-
?