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Literature summary extracted from
- Cyclic nucleotide phosphodiesterase in silkworm: purification and properties (1974), Biochim. Biophys. Acta, 370, 227-241.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.16 | Ba2+ | - |
Bombyx mori |  |
| 3.1.4.16 | Mn2+ | - |
Bombyx mori | |
| 3.1.4.16 | Zn2+ | - |
Bombyx mori | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.16 | Mg2+ | 1-10 mM, slight increase of activity | Bombyx mori | |
| 3.1.4.16 | additional information | no requirement for metal ions | Bombyx mori |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.4.16 | Bombyx mori | - |
activity towards 2',3'-cyclic nucleotides and 3',5'-cyclic nucleotides are associated with the same protein molecule | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.4.16 | partial, activity towards 2',3'-cyclic nucleotides and 3',5'-cyclic nucleotides are associated with the same protein molecule | Bombyx mori |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.4.16 | larva | - |
Bombyx mori | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.16 | cyclic 2',3'-AMP + H2O | - |
Bombyx mori | 3'-AMP | - |
? | |
| 3.1.4.16 | cyclic 2',3'-CMP + H2O | - |
Bombyx mori | 3'-CMP | - |
? | |
| 3.1.4.16 | cyclic 2',3'-UMP + H2O | - |
Bombyx mori | 3'-UMP | - |
? | |
| 3.1.4.16 | cyclic 3',5'-AMP + H2O | at 9.1% of the activity with 2',3'-cyclic AMP | Bombyx mori | 5'-AMP | - |
? | |
| 3.1.4.16 | cyclic 3',5'-GMP + H2O | at 9.2% of the activity with 3',5'-cyclic AMP | Bombyx mori | 5'-GMP | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.16 | 45 | - |
hydrolysis of 2',3'-cyclic AMP | Bombyx mori |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.16 | 7.4 | 8 | hydrolysis of 2',3'-cyclic AMP, 2',3'-GMP, 2',3'-CMP and 2',3'-UMP | Bombyx mori |
| 3.1.4.16 | 8.2 | - |
hydrolysis of 3',5'-cyclic AMP | Bombyx mori |
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