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Literature summary extracted from

  • Mansat, V.; Bettaieb, A.; Levade, T.; Laurent, G.; Jaffrezou, J.P.
    Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin (1997), FASEB J., 11, 695-702.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.4.12 daunorubicin
-
Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.12 dichloroisocoumarin
-
Homo sapiens
3.1.4.12 N-tosyl-L-phenylalanyl chloromethyl ketone
-
Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.12 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.12 HL-60 cell
-
Homo sapiens
-
3.1.4.12 U-937 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.12 sphingomyelin + H2O
-
Homo sapiens N-acylsphingosine + choline phosphate
-
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