Any feedback?
Literature summary extracted from
- Alkaline sphingomyelinase activity in rat gastrointestinal tract: distribution and characteristics (1995), Biochim. Biophys. Acta, 1259, 49-55.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.12 | Triton X-100 | dose dependent, alkaline sphingomyelinase | Rattus norvegicus |  |
| 3.1.4.12 | Trypsin | inactivation in pancreas, liver, duodenum but not in intestine, acid sphingomyelinase | Rattus norvegicus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.4.12 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.4.12 | intestine | gastrointestinal tract | Rattus norvegicus | - |
| 3.1.4.12 | additional information | maximum activity in the distal jejunum, little activity in bile, liver, pancreas after trypsin treatment | Rattus norvegicus | - |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.12 | 9 | - |
jejunum | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
