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Literature summary extracted from

  • Mazzoni, M.; Bertagnolo, V.; Neri, L.M.; Carini, C.; Marchisio, M.; Milani, D.; Manzoli, F.A.; Capitani, S.
    Discrete subcellular localization of phosphoinositidase C beta, gamma and delta in PC12 rat pheochromocytoma cells (1992), Biochem. Biophys. Res. Commun., 187, 114-120.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.11 cytoplasm phosphoinositidase C delta is restricted to the cytopasm Rattus norvegicus 5737
-
3.1.4.11 nucleus phosphoinositidase C beta is exclusively localized in the nucleus Rattus norvegicus 5634
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.11 Ca2+ maximally active with Ca2+ concentrations ranging from endogenous levels to 1 mM for the substrates phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.11 additional information Rattus norvegicus the inositol lipid breakdown is controlled by different phosphoinositidase C isoenzymes in various cell compartments ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.11 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.11 PC-12 cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.11 additional information the inositol lipid breakdown is controlled by different phosphoinositidase C isoenzymes in various cell compartments Rattus norvegicus ?
-
 ?
3.1.4.11 phosphatidylinositol + H2O
-
 Rattus norvegicus ?
-
 ?
3.1.4.11 phosphatidylinositol 4,5-bisphosphate + H2O
-
 Rattus norvegicus D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
 ?
3.1.4.11 phosphatidylinositol 4-phosphate
-
 Rattus norvegicus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.4.11 7
-
-
 Rattus norvegicus