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Literature summary extracted from

  • Gite, S.; Reddy, G.; Shankar, V.
    Active-site characterization of S1 nuclease I (1992), Biochem. J., 285, 489-494.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.30.1 amino group modification at pH 8.0, 65-70% loss of initial activity towards ssDNA, RNA and 3'-AMP after modification of amino groups, lysine residues, with 0.5 mM 2,4,6-trinitrobenzenesulfonic acid Aspergillus oryzae
3.1.30.1 citraconylation reversible block of amino groups, lysine residues, by citraconic anhydride Aspergillus oryzae
3.1.30.1 reductive methylation modification of lysine residues into N,N'-dimethyl lysine Aspergillus oryzae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.30.1 DNA + H2O Aspergillus oryzae
-
5'-phosphomononucleotides + 5'-phosphooligonucleotides
-
?
3.1.30.1 RNA + H2O Aspergillus oryzae
-
5'-phosphomononucleotides + 5'-phosphooligonucleotides
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.30.1 Aspergillus oryzae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.30.1
-
Aspergillus oryzae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.30.1 3'-AMP + H2O
-
Aspergillus oryzae adenosine + phosphate
-
?
3.1.30.1 DNA + H2O
-
Aspergillus oryzae 5'-phosphomononucleotides + 5'-phosphooligonucleotides
-
?
3.1.30.1 RNA + H2O
-
Aspergillus oryzae 5'-phosphomononucleotides + 5'-phosphooligonucleotides
-
?
3.1.30.1 ssDNA + H2O
-
Aspergillus oryzae 5'-phosphomononucleotides + 5'-phosphooligonucleotides
-
?