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Literature summary extracted from

  • Mithieux, G.; Daniele, N.; Payrastre, B.; Zitoun, C.
    Liver microsomal glucose-6-phosphatase is competitively inhibited by the lipid products of phosphatidylinositol 3-kinase (1998), J. Biol. Chem., 273, 17-19.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.9 alpha-phosphatidylinositol 3-monophosphate
-
 Rattus norvegicus
3.1.3.9 alpha-phosphatidylinositol 4,5-diphosphate
-
 Rattus norvegicus
3.1.3.9 alpha-phosphatidylinositol 4-monophosphate
-
 Rattus norvegicus
3.1.3.9 L-alpha-phosphatidylinositol 3,4,5-trisphosphate
-
 Rattus norvegicus
3.1.3.9 L-alpha-phosphatidylinositol 3,4-diphosphate
-
 Rattus norvegicus
3.1.3.9 phosphatidylinositol
-
 Rattus norvegicus
3.1.3.9 phosphoinositides in order of decreasing efficiency: phosphatidylinositol, L-alpha-phosphatidylinositol 3,4,5-trisphosphate, L-alpha-phosphatidylinositol 3,4-diphosphate, alpha-phosphatidylinositol 4,5-diphosphate, alpha-phosphatidylinositol 3-monophosphate, alpha-phosphatidylinositol 4-monophosphate, phosphatidylinositol. Mechanism of inhibition with alpha-phosphatidylinositol 3,4-diphosphate, alpha-phosphatidylinositol 4,5-diphosphate or L-alpha-phosphatidylinositol 3,4,5-trisphosphate is competitive Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.9 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.9 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.9 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.9 D-glucose 6-phosphate + H2O
-
 Rattus norvegicus D-glucose + phosphate
-
 ?