BRENDA - Enzyme Database

Developmental changes in enzymes involved in dolichyl phosphate metabolism in cultured embryonic rat brain cells

Bhat, N.R.; Frank, D.W.; Wolf, M.J.; Waechter, C.J.; J. Neurochem. 56, 339-344 (1991)

Data extracted from this reference:

KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.6.1.43
0.025
-
dolichyl diphosphate
day 4 of embryonic development
Rattus norvegicus
3.6.1.43
0.166
-
dolichyl diphosphate
day 22 of embryonic development
Rattus norvegicus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.6.1.43
dolichyl diphosphate + H2O
Rattus norvegicus
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
dolichyl phosphate + phosphate
-
Rattus norvegicus
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.3.51
Rattus norvegicus
-
-
-
3.6.1.43
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.51
brain
embryonic brain cells, the enzyme is present at relatively low levels for the first 9 days in culture, but it increases steadily between days 9 and 30
Rattus norvegicus
-
3.6.1.43
brain
embryonic
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
3.6.1.43
additional information
-
increases significantly during day 12-25 of embryonic development
Rattus norvegicus
3.6.1.43
0.003
-
day 4 of embryonic development
Rattus norvegicus
3.6.1.43
0.032
-
day 22 of embryonic development
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.51
dolichyl phosphate + H2O
-
134921
Rattus norvegicus
dolichol + phosphate
-
-
-
?
3.6.1.43
dolichyl diphosphate + H2O
-
134921
Rattus norvegicus
dolichyl phosphate + phosphate
-
134921
Rattus norvegicus
?
3.6.1.43
dolichyl diphosphate + H2O
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
134921
Rattus norvegicus
dolichyl phosphate + phosphate
-
134921
Rattus norvegicus
?
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.6.1.43
0.025
-
dolichyl diphosphate
day 4 of embryonic development
Rattus norvegicus
3.6.1.43
0.166
-
dolichyl diphosphate
day 22 of embryonic development
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.6.1.43
dolichyl diphosphate + H2O
Rattus norvegicus
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
dolichyl phosphate + phosphate
-
Rattus norvegicus
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.51
brain
embryonic brain cells, the enzyme is present at relatively low levels for the first 9 days in culture, but it increases steadily between days 9 and 30
Rattus norvegicus
-
3.6.1.43
brain
embryonic
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
3.6.1.43
additional information
-
increases significantly during day 12-25 of embryonic development
Rattus norvegicus
3.6.1.43
0.003
-
day 4 of embryonic development
Rattus norvegicus
3.6.1.43
0.032
-
day 22 of embryonic development
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.51
dolichyl phosphate + H2O
-
134921
Rattus norvegicus
dolichol + phosphate
-
-
-
?
3.6.1.43
dolichyl diphosphate + H2O
-
134921
Rattus norvegicus
dolichyl phosphate + phosphate
-
134921
Rattus norvegicus
?
3.6.1.43
dolichyl diphosphate + H2O
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
134921
Rattus norvegicus
dolichyl phosphate + phosphate
-
134921
Rattus norvegicus
?