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Literature summary extracted from
- Developmental changes in enzymes involved in dolichyl phosphate metabolism in cultured embryonic rat brain cells (1991), J. Neurochem., 56, 339-344.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.6.1.43 | 0.025 | - |
dolichyl diphosphate | day 4 of embryonic development | Rattus norvegicus |  |
| 3.6.1.43 | 0.166 | - |
dolichyl diphosphate | day 22 of embryonic development | Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.43 | dolichyl diphosphate + H2O | Rattus norvegicus | involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate | dolichyl phosphate + phosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.51 | Rattus norvegicus | - |
- |
- |
| 3.6.1.43 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.3.51 | brain | embryonic brain cells, the enzyme is present at relatively low levels for the first 9 days in culture, but it increases steadily between days 9 and 30 | Rattus norvegicus | - |
| 3.6.1.43 | brain | embryonic | Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.43 | additional information | - |
increases significantly during day 12-25 of embryonic development | Rattus norvegicus |
| 3.6.1.43 | 0.003 | - |
day 4 of embryonic development | Rattus norvegicus |
| 3.6.1.43 | 0.032 | - |
day 22 of embryonic development | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.51 | dolichyl phosphate + H2O | - |
Rattus norvegicus | dolichol + phosphate | - |
? | |
| 3.6.1.43 | dolichyl diphosphate + H2O | - |
Rattus norvegicus | dolichyl phosphate + phosphate | - |
? | |
| 3.6.1.43 | dolichyl diphosphate + H2O | involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate | Rattus norvegicus | dolichyl phosphate + phosphate | - |
? | |
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