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Literature summary extracted from

  • Boscoboinik, D.O.; Morera, S.; Belocopitow, E.
    Dolichyl phosphate phosphatase in rat liver microsomes. Avoidance of the use of detergent in testing the effect of phospholipids on dolichyl phosphate phosphatase (1984), Biochim. Biophys. Acta, 794, 41-48.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.51 ADP activates Rattus norvegicus
3.1.3.51 AMP activates Rattus norvegicus
3.1.3.51 ATP activates Rattus norvegicus
3.1.3.51 EDTA activates Rattus norvegicus
3.1.3.51 glucose 1-phosphate activates Rattus norvegicus
3.1.3.51 glucose 6-phosphate activates Rattus norvegicus
3.1.3.51 phosphatidylcholine activates Rattus norvegicus
3.1.3.51 phosphatidylethanolamine activates Rattus norvegicus
3.1.3.51 sphingomyelin activates Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.51 NaF slight inhibition Rattus norvegicus
3.1.3.51 phosphate
-
 Rattus norvegicus
3.1.3.51 phosphatidic acid 0.00006 mg, 50% inhibition Rattus norvegicus
3.1.3.51 phosphatidylinositol
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.51 microsome
-
 Rattus norvegicus
-
-
3.1.3.51 plasma membrane
-
 Rattus norvegicus 5886
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.51 300000
-
 gel filtration, sucrose density gradient centrifugation Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.51 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.51 liver
-
 Rattus norvegicus
-

Storage Stability

EC Number Storage Stability Organism
3.1.3.51 -20°C, 24 h, 35% loss of activity Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.51 dolichyl phosphate + H2O
-
 Rattus norvegicus dolichol + phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.3.51 30
-
 dolichyl phosphate solution Rattus norvegicus
3.1.3.51 37
-
 dolichyl phosphate particles Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.3.51 0.00006
-
 phosphatidic acid
-
 Rattus norvegicus