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Literature summary extracted from

  • Krakower, G.R.; Kim, K.H.
    Purification and properties of acetyl-CoA carboxylase phosphatase (1981), J. Biol. Chem., 256, 2408-2413.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.44 acetyl-CoA carboxylase inhibits dephosphorylation of phosphoprotamine Rattus norvegicus
3.1.3.44 F- 50 mM, no effect on dephosphorylation of [acetyl-CoA carboxylase], strong inhibition of the dephosphorylation of [phosphorylase a]-phosphate Rattus norvegicus
3.1.3.44 phosphate strong inhibitor when phosphoprotamine or [phosphorylase a]-phosphate is the substrate, the effect is far less apparent when [acetyl-CoA carboxylase]-phosphate is used as the substrate Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.44 0.0015
-
 [acetyl-CoA carboxylase]-phosphate
-
 Rattus norvegicus
3.1.3.44 0.037
-
 [glycogen phosphorylase A]-phosphate
-
 Rattus norvegicus
3.1.3.44 0.076
-
 phosphoprotamine
-
 Rattus norvegicus
3.1.3.44 1.34
-
 p-nitrophenyl phosphate
-
 Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.44 71000
-
 gel filtration Rattus norvegicus

Organic Solvent Stability

EC Number Organic Solvent Comment Organism
3.1.3.44 Ethanol stable in presence of ethanol over long periods of time Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.44 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.44
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.44 epididymis
-
 Rattus norvegicus
-
3.1.3.44 fat pad
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.3.44 871
-
-
 Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
3.1.3.44 4°C, stable for several weeks Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.44 p-nitrophenyl phosphate + H2O
-
 Rattus norvegicus p-nitrophenol + phosphate
-
 ?
3.1.3.44 phosphoprotamine + H2O
-
 Rattus norvegicus protamine + phosphate
-
 ?
3.1.3.44 [3-hydroxy-3-methylglutaryl-CoA reductase]-phosphate + H2O
-
 Rattus norvegicus 3-hydroxy-3-methylglutaryl-CoA reductase + phosphate
-
 ?
3.1.3.44 [acetyl-CoA carboxylase]-phosphate + H2O
-
 Rattus norvegicus acetyl-CoA carboxylase + phosphate
-
 ?
3.1.3.44 [glycogen phosphorylase A]-phosphate
-
 Rattus norvegicus [glycogen phosphorylase A] + phosphate
-
 ?
3.1.3.44 [glycogen-phosphorylase a]-phosphate + H2O
-
 Rattus norvegicus glycogen-phosphorylase a + phosphate
-
 ?
3.1.3.44 [glycogen-synthase]-phosphate + H2O
-
 Rattus norvegicus glycogen-synthase + phosphate
-
 ?
3.1.3.44 [phosphoralase a]-phosphate + H2O
-
 Rattus norvegicus phosphoralase a + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.44 monomer 1 * 71000, SDS-PAGE Rattus norvegicus