EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.3.36 | 0.028 | - |
Inositol 1,3,4,5-tetrakisphosphate | - |
Homo sapiens | |
3.1.3.36 | 0.123 | - |
Inositol 1,4,5-trisphosphate | - |
Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.3.36 | lysosome | enzyme is associated with the lysosomal membrane | Homo sapiens | 5764 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.36 | additional information | Homo sapiens | the X-chromosome encoded enzyme is deficient in oculocerebrorenal syndrome | ? | - |
? | |
3.1.3.36 | additional information | Homo sapiens | the enzyme may function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-diphosphate that is associated with lysosomes | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.36 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.3.36 | kidney cell line | cell lines from kidney proximal tubules of a patient with Lowe syndrome and a normal individual | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.36 | inositol 1,3,4,5-tetrakisphosphate + H2O | - |
Homo sapiens | inositol 1,3,4-trisphosphate + phosphate | - |
? | |
3.1.3.36 | additional information | the X-chromosome encoded enzyme is deficient in oculocerebrorenal syndrome | Homo sapiens | ? | - |
? | |
3.1.3.36 | additional information | the enzyme may function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-diphosphate that is associated with lysosomes | Homo sapiens | ? | - |
? | |
3.1.3.36 | myo-inositol 1,4,5-trisphosphate + H2O | - |
Homo sapiens | inositol 1,4-diphosphate + phosphate | - |
? | |
3.1.3.36 | myo-inositol 3,4,5-trisphosphate + H2O | - |
Homo sapiens | ? | - |
? | |
3.1.3.36 | phosphatidyl-myo-inositol 4,5-bisphosphate + H2O | - |
Homo sapiens | phosphatidylinositol 4-phosphate + phosphate | - |
? |