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Literature summary extracted from

  • Karpetsky, T.P.; Shriver, K.K.; Levy, C.C.
    Covalent linkage of poly(A) to RNA produces a molecule altered in both structure and susceptibility to ribonuclease-mediated hydrolysis (1980), J. Biol. Chem., 255, 2713-2721.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.6.1.21 Ni2+
-
 Enterobacter sp.
4.6.1.21 Poly(A) rRNA-linked poly(A) is a more effective inhibitor than the free homopolymer, inhibition reversable by high ionic strength Enterobacter sp.

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.6.1.21 Co2+ reverses poly(A)-induced inhibition Enterobacter sp.
4.6.1.21 Mg2+ reverses poly(A)-induced inhibition at a concentration of 0.05 mM Enterobacter sp.
4.6.1.21 Ni2+ inhibitory even at low concentrations Enterobacter sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.21 RNA + H2O Enterobacter sp. preferential cleavage at CpA nucleoside 3'-phosphates and 3'-phosphooligonucleotides and 2',3'-cyclic phosphates
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.21 Enterobacter sp.
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.21 additional information not: homopolymers of A, U or G Enterobacter sp. ?
-
 ?
4.6.1.21 RNA + H2O preferential cleavage at CpA Enterobacter sp. nucleoside 3'-phosphates and 3'-phosphooligonucleotides and 2',3'-cyclic phosphates
-
 ?