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Literature summary extracted from

  • Yamasaki, M.; Arima, K.
    ATP-inhibited ribonuclease of Bacillus subtilis. II. Effect of adenosine triphosphate and other compounds (1970), Biochim. Biophys. Acta, 209, 475-483.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.6.1.22 ADP inhibition influenced by pH, enhanced inhibition at pH 7.5; less effective than ATP but more potent in the crude ribonuclease preparation Bacillus subtilis
4.6.1.22 ATP inhibition influenced by pH, enhanced inhibition at pH 7.5 Bacillus subtilis
4.6.1.22 calf thymus native DNA slight Bacillus subtilis
4.6.1.22 dATP inhibition influenced by pH, enhanced inhibition at pH 7.5 Bacillus subtilis
4.6.1.22 diazo-1H-tetrazol
-
 Bacillus subtilis
4.6.1.22 GDP less effective than ATP, competitive inhibitor, inhibition influenced by pH, enhanced inhibition at pH 7.0 Bacillus subtilis
4.6.1.22 GTP less effective than ATP, competitive inhibitor, inhibition influenced by pH, enhanced inhibition at pH 7.0 Bacillus subtilis
4.6.1.22 UDP slight at pH 7.0 Bacillus subtilis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.6.1.22 Ca2+ slight Bacillus subtilis
4.6.1.22 Co2+ slight Bacillus subtilis
4.6.1.22 Cu2+
-
 Bacillus subtilis
4.6.1.22 Hg2+
-
 Bacillus subtilis
4.6.1.22 Ni2+ slight Bacillus subtilis
4.6.1.22 Zn2+ slight Bacillus subtilis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.6.1.22 25000
-
 gel filtration Bacillus subtilis
4.6.1.22 25000
-
 allosteric mechanism Bacillus subtilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.22 RNA + H2O Bacillus subtilis
-
 2',3'-cyclic nucleotides
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.22 Bacillus subtilis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.22 RNA + H2O
-
 Bacillus subtilis 2',3'-cyclic nucleotides
-
 ?
4.6.1.22 RNA + H2O e.g. yeast RNA Bacillus subtilis 2',3'-cyclic nucleotides
-
 ?