Literature summary extracted from

Szeberenyi, J.; Roy, M.K.; Vaidya, H.C.; Apirion, D.
7S RNA, containing 5S ribosomal RNA and the termination stem, is a specific substrate for the two RNA processing enzymes RNase III and RNase E (1984), Biochemistry, 23, 2952-2957.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.1.26.3	double-stranded RNA + H2O	Escherichia coli	cleaves multimeric tRNA precursor at the spacer region, also involved in processing of precursor rRNA, hnRNA and early T7-mRNA. Also cleaves double-stranded DNA and single-stranded RNA	5'-phosphooligonucleotides	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.26.3	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.26.3	double-stranded RNA + H2O	-	Escherichia coli	5'-phosphooligonucleotides	-	?
3.1.26.3	double-stranded RNA + H2O	cleaves multimeric tRNA precursor at the spacer region, also involved in processing of precursor rRNA, hnRNA and early T7-mRNA. Also cleaves double-stranded DNA and single-stranded RNA	Escherichia coli	5'-phosphooligonucleotides	-	?
3.1.26.3	ribosomal RNA + H2O	7S RNA is cleaved	Escherichia coli	smaller precursor rRNA	-	?
3.1.26.3	tRNA + H2O	-	Escherichia coli	5'-phosphooligonucleotides	-	?

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Release 2023.1 (January 2023)