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Literature summary extracted from

  • Suck, D.; Oefner, C.; Kabsch, W.
    Three-dimensional structure of bovine pancreatic DNase I at 2.5 angström resolution (1984), EMBO J., 3, 2423-2430.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.1.21.1 2.5 A resolution, alpha-beta-protein, carbohydrate attached to Asn18, active centre close to His 131 Bos taurus
3.1.21.1 complex between DNase I and uncleaved octamer duplex DNA, 2.3 A resolution Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.21.1 Ca2+ 2 Ca2+ bound to the enzyme under crystallization conditions Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.21.1 double-stranded DNA + H2O Bos taurus
-
 5'-phosphooligonucleotides + ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.21.1 Bos taurus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.21.1 glycoprotein DNase A with a neutral carbohydrate side-chain, DNase B with a sialic acid carbohydrate side-chain Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.21.1 pancreas
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.21.1 double-stranded DNA + H2O
-
 Bos taurus 5'-phosphooligonucleotides + ?
-
 ?