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Literature summary extracted from

  • Bernardi, A.; Bernardi, G.
    Spleen acid exonuclease (1971), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 4, 329-336.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.16.1 EDTA with RNA core as substrate Bos taurus
3.1.16.1 sulfhydryl reagents with RNA core as substrate Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.16.1 acetylation complete inhibition by acetylation of the 2'-OH of tRNA Bos taurus
3.1.16.1 arsenite weak inhibitor with RNA core as substrate Bos taurus
3.1.16.1 Cu2+
-
 Bos taurus
3.1.16.1 Deoxyribonucleoside 3'-phosphates
-
 Bos taurus
3.1.16.1 F- weak inhibitor with RNA core as substrate Bos taurus
3.1.16.1 glycosylation no activity with glycosylated oligonucleotides obtained from T4 phage DNA Bos taurus
3.1.16.1 Hg2+ with RNA core as substrate Bos taurus
3.1.16.1 Mg2+ with RNA core as substrate Bos taurus
3.1.16.1 Mn2+ with RNA core as substrate Bos taurus
3.1.16.1 Zn2+ with RNA core as substrate Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.1.16.1 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.16.1 spleen
-
 Bos taurus
-

Storage Stability

EC Number Storage Stability Organism
3.1.16.1 -15°C, in 50% glycerol Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.16.1 4-nitrophenyl phosphate
-
 Bos taurus 4-nitrophenol + phosphate
-
 ?
3.1.16.1 bis-(4-nitrophenyl)phosphate + H2O
-
 Bos taurus 4-nitrophenyl phosphate + 4-nitrophenol
-
 ?
3.1.16.1 DNA + H2O denatured only, no native or double stranded Bos taurus deoxyribonucleoside 3'-phosphates
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.16.1 5.8
-
 substrate bis-(p-nitrophenyl) phosphate in 0.25 M succinate buffer Bos taurus