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Literature summary extracted from

  • Karu, A.E.; MacKay, V.; Goldmark, P.J.; Linn, S.
    The recBC deoxyribonuclease of Escherichia coli K-12. Substrate specificity and reaction intermediates (1973), J. Biol. Chem., 248, 4874-4884.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.11.5 bovine serum albumin 2-3fold stimulation Escherichia coli
3.1.11.5 RNA-DNA hybrid activates ATPase only Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.11.5 ATP + H2O Escherichia coli DNA dependent ADP + phosphate
-
 ?
3.1.11.5 double-stranded DNA + H2O Escherichia coli ATP-dependent exonuclease single-stranded DNA fragments
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.11.5 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.11.5 ATP + H2O linear DNA dependent Escherichia coli ADP + phosphate
-
 ?
3.1.11.5 ATP + H2O RNA-DNA hybrids or cross-linked DNA can serve as cofactors Escherichia coli ADP + phosphate
-
 ?
3.1.11.5 ATP + H2O complete inhibition of DNAse activity has no effect on ATPase activity Escherichia coli ADP + phosphate
-
 ?
3.1.11.5 ATP + H2O DNA dependent Escherichia coli ADP + phosphate
-
 ?
3.1.11.5 double-stranded DNA + H2O acts on native, heat-denatured and glucosylated DNA Escherichia coli single-stranded DNA fragments
-
 ?
3.1.11.5 double-stranded DNA + H2O a gap of 5 nucleotides in circular DNA needed for activity Escherichia coli single-stranded DNA fragments
-
 ?
3.1.11.5 double-stranded DNA + H2O no activity on circular DNA Escherichia coli single-stranded DNA fragments
-
 ?
3.1.11.5 double-stranded DNA + H2O ATP-dependent exonuclease Escherichia coli single-stranded DNA fragments
-
 ?