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Literature summary extracted from

  • Brody, R.S.; Doherty, K.G.; Zimmermann, P.D.
    Processivity and kinetics of the reaction of exonuclease I from Escherichia coli with polydeoxyribonucleotides (1986), J. Biol. Chem., 261, 7136-7143.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.11.1 expression in Escherichia coli Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.11.1 0.1
-
oligonucleotide (polydA)4 inverse dependence with polymer size Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.11.1 single-stranded oligodeoxyribonucleotide + H2O Escherichia coli nucleic acid binding requires two distinct recognition sites in oligodeoxyribonucleotides single-stranded oligodeoxyribonucleotide + nucleoside 5'-monophosphate
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.11.1 Escherichia coli
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.11.1 cell culture
-
Escherichia coli
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.11.1 oligonucleotide (polydA)4 + H2O
-
Escherichia coli ?
-
?
3.1.11.1 single-stranded oligodeoxyadenylate + H2O
-
Escherichia coli single-stranded oligodeoxyadenylate + adenosine 5'-monophosphate mainly degraded to 9-mers ?
3.1.11.1 single-stranded oligodeoxycytidylate + H2O
-
Escherichia coli single-stranded oligodeoxycytidylate + cytidyl 5'-monophosphate degradation of p(dC) polymers to products from 10-mers to 6-mers, mainly degraded to 8-mers ?
3.1.11.1 single-stranded oligodeoxyribonucleotide + H2O
-
Escherichia coli single-stranded oligodeoxyribonucleotide + nucleoside 5'-monophosphate
-
?
3.1.11.1 single-stranded oligodeoxyribonucleotide + H2O nucleic acid binding requires two distinct recognition sites in oligodeoxyribonucleotides Escherichia coli single-stranded oligodeoxyribonucleotide + nucleoside 5'-monophosphate
-
?
3.1.11.1 single-stranded oligodeoxythymidylate + H2O
-
Escherichia coli single-stranded oligodeoxythymidylate + thymidine 5'-monophosphate mainly degraded to 9-mers ?