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Literature summary extracted from

  • Sahu, S.; Lynn, W.S.
    Characterization of phospholipase A from pulmonary secretions of patients with alveolar proteinosis (1977), Biochim. Biophys. Acta, 489, 307-317.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.4 deoxycholate
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.4 Ca2+
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.4 75000
-
 SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.4 phospholipids + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.4 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.4 ion-exchange chromatography, gel-filtration Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.4 lung pulmonary secretions Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.4 1140
-
 substrate: egg yolk emulsion Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.1.1.4 -20°C, lyophilized enzyme, no loss of activity over 3 months Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.4 1,2-dimyristoyl-sn-phosphatidylcholine + H2O
-
 Homo sapiens 1-myristoyl-phosphorylcholine + myristic acid
-
 ?
3.1.1.4 1,2-dipalmitoyl-phosphatidylcholine + H2O
-
 Homo sapiens 1-palmitoyl-glycerophosphorylcholine + palmitic acid
-
 ?
3.1.1.4 1,2-dipalmitoyl-phosphatidylethanolamine + H2O
-
 Homo sapiens 1-palmitoyl-phosphatidylethanolamine + palmitic acid
-
 ?
3.1.1.4 1-oleoyl-2-palmitoyl-phosphatidylcholine + H2O
-
 Homo sapiens 1-oleoyl-phosphatidylcholine + palmitic acid
-
 ?
3.1.1.4 1-palmitoyl-2-oleoylphosphatidylcholine + H2O
-
 Homo sapiens 1-palmitoyl-glycerophosphocholine + oleic acid
-
 ?
3.1.1.4 diarachidonylphosphatidylcholine + H2O
-
 Homo sapiens arachidonylphosphatidylcholine + arachidonic acid
-
 ?
3.1.1.4 phosphatidylcholine + H2O
-
 Homo sapiens 1-acylglycerophosphocholine + fatty acid
-
 ?
3.1.1.4 phosphatidylethanolamine + H2O
-
 Homo sapiens 1-acylglycerophosphorylethanolamine + fatty acid
-
 ?
3.1.1.4 phosphatidylglycerol + H2O
-
 Homo sapiens 1-acylglycerol + fatty acid
-
 ?
3.1.1.4 phospholipids + H2O
-
 Homo sapiens ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.4 7.5 8.5 substrate: egg yolk emulsion Homo sapiens