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Literature summary extracted from

  • Ghomashchi, F.; Yu, B.Z.; Mihelich, E.D.; Jain, M.K.; Gelb, M.H.
    Kinetic characterization of phospholipase A2 modified by manoalogue (1991), Biochemistry, 30, 9559-9569.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.4 1-hexadecyl-3-trifluoroethylglycero-sn-2-phosphomethanol MJ33, competitive inhibitor Apis mellifera
3.1.1.4 1-hexadecyl-3-trifluoroethylglycero-sn-2-phosphomethanol MJ33, competitive inhibitor Naja naja
3.1.1.4 1-hexadecyl-3-trifluoroethylglycero-sn-2-phosphomethanol MJ33, competitive inhibitor Sus scrofa
3.1.1.4 manoalogue synthetic analogue of the sea sponge-derived manoalide, time dependent irreversible loss of activity: modification of lysine residues Apis mellifera
3.1.1.4 manoalogue synthetic analogue of the sea sponge-derived manoalide, time dependent irreversible loss of activity: modification of lysine residues Naja naja
3.1.1.4 manoalogue synthetic analogue of the sea sponge-derived manoalide, time dependent irreversible loss of activity: modification of lysine residues Sus scrofa
3.1.1.4 omega-bromo-4-nitroacetophenone
-
 Apis mellifera
3.1.1.4 omega-bromo-4-nitroacetophenone
-
 Naja naja
3.1.1.4 omega-bromo-4-nitroacetophenone
-
 Sus scrofa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.4 Ca2+
-
 Sus scrofa
3.1.1.4 Ca2+
-
 Apis mellifera
3.1.1.4 Ca2+
-
 Naja naja

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.4 phospholipids + H2O Sus scrofa
-
 ?
-
 ?
3.1.1.4 phospholipids + H2O Naja naja
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.4 Apis mellifera
-
-
-
3.1.1.4 Naja naja
-
 cobra
-
3.1.1.4 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.4 pancreas
-
 Sus scrofa
-
3.1.1.4 venom
-
 Apis mellifera
-
3.1.1.4 venom
-
 Naja naja
-

Storage Stability

EC Number Storage Stability Organism
3.1.1.4 -20°C Sus scrofa
3.1.1.4 -20°C Apis mellifera
3.1.1.4 -20°C Naja naja

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.4 1,2-dimyristol-sn-glycero-phosphomethanol lithium salt + H2O
-
 Sus scrofa myristic acid + 1-myristoyl-sn-glycerophosphomethanol
-
 ?
3.1.1.4 1,2-dimyristol-sn-glycero-phosphomethanol lithium salt + H2O
-
 Apis mellifera myristic acid + 1-myristoyl-sn-glycerophosphomethanol
-
 ?
3.1.1.4 1,2-dimyristol-sn-glycero-phosphomethanol lithium salt + H2O
-
 Naja naja myristic acid + 1-myristoyl-sn-glycerophosphomethanol
-
 ?
3.1.1.4 phospholipids + H2O
-
 Sus scrofa ?
-
 ?
3.1.1.4 phospholipids + H2O
-
 Naja naja ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.4 monomer
-
 Sus scrofa
3.1.1.4 monomer
-
 Apis mellifera
3.1.1.4 monomer
-
 Naja naja