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Literature summary extracted from

  • Minami, T.; Tojo, H.; Shinomura, Y.; Matsuzawa, Y.; Okamoto, M.
    Purification and characterization of a phospholipase A2 from human ileal mucosa (1993), Biochim. Biophys. Acta, 1170, 125-130.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.4 Ca2+
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.4 14000
-
 heparin-sepharose affinity chromatography, SDS-PAGE after digestion with thrombin, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.4 phospholipids + H2O Homo sapiens eicosanoids ?
-
 ?
3.1.1.4 phospholipids + H2O Homo sapiens inflammatory diseases ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.4 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.4 column chromatography, 4500fold Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.4 cecum mucosa
-
 Homo sapiens
-
3.1.1.4 colonic mucosa ascending, transverse, descending, sigmoid colon Homo sapiens
-
3.1.1.4 ileal mucosa
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.4 0.0062
-
 sigmoid colon mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol Homo sapiens
3.1.1.4 0.0071
-
 cecal mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol Homo sapiens
3.1.1.4 0.0072
-
 ascending colon mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol Homo sapiens
3.1.1.4 0.0078
-
 transverse colon mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol Homo sapiens
3.1.1.4 0.0092
-
 descending colon mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol Homo sapiens
3.1.1.4 0.0509
-
 ileal mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol Homo sapiens
3.1.1.4 306
-
 purified PLA2 from ileal mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.4 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine + H2O
-
 Homo sapiens 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol + H2O
-
 ?
3.1.1.4 1-palmitoyl-2-oleoylphosphatidylcholine + H2O
-
 Homo sapiens 1-palmitoyl-glycerophosphocholine + oleic acid
-
 ?
3.1.1.4 phospholipids + H2O eicosanoids Homo sapiens ?
-
 ?
3.1.1.4 phospholipids + H2O inflammatory diseases Homo sapiens ?
-
 ?