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Literature summary extracted from
- Purification of a basic phospholipase A2 from Indian Saw-Scawled Viper (Echis carinatus) venom: characterization of antigenic, catalytic and pharmacological properties (1994), Toxicon, 32, 1187-1196.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.4 | anti-peptide antibody | - |
Echis carinatus |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.1.4 | 0.25 | - |
phosphatidylcholine | - |
Echis carinatus |  |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.4 | Ca2+ | - |
Echis carinatus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.4 | 13500 | - |
gel filtration | Echis carinatus |
| 3.1.1.4 | 14000 | - |
SDS-PAGE | Echis carinatus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.4 | phospholipids + H2O | Echis carinatus | presynaptic neurotoxicity of neutral PLA2 | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.4 | Echis carinatus | - |
Indian Saw-Scawled Viper | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.1.4 | column chromatography, electrophoresis, EC-IV-PLA2, 2.3fold | Echis carinatus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.4 | venom | - |
Echis carinatus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.4 | 0.4 | - |
substrate: phosphatidylcholine | Echis carinatus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.4 | phosphatidylcholine + H2O | - |
Echis carinatus | 1-acylglycerophosphocholine + fatty acid | - |
? | |
| 3.1.1.4 | phospholipids + H2O | presynaptic neurotoxicity of neutral PLA2 | Echis carinatus | ? | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.4 | 50 | 55 | EC-IV-PLA2 | Echis carinatus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.4 | 7.5 | 8 | EC-IV-PLA2 | Echis carinatus |
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