EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.13 | sodium taurocholic acid | - |
Homo sapiens | |
3.1.1.13 | sodium taurocholic acid | - |
Rattus sp. |
EC Number | Cloned (Comment) | Organism |
---|---|---|
3.1.1.13 | overexpression in baculovirus-infected Sf9 cells | Rattus sp. |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.1.1.13 | H435Q | cholesterol esterase activity abolished , lipoamidase activity uneffected | Rattus sp. |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.1.13 | 0.011 | - |
lipoyl 4-aminobenzoate | mutant cholesterol esterase | Rattus sp. | |
3.1.1.13 | 0.015 | - |
Triacetin | native cholesterol esterase | Rattus sp. | |
3.1.1.13 | 0.024 | - |
lipoyl 4-aminobenzoate | native cholesterol esterase | Rattus sp. |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.1.13 | extracellular | - |
Homo sapiens | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.1.13 | 72000 | - |
calculation from sequence of cDNA | Rattus sp. |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.13 | cholesteryl esters + H2O | Homo sapiens | shows also lipoamidase activity | cholesterol + fatty acid | - |
? | |
3.1.1.13 | cholesteryl esters + H2O | Rattus sp. | shows also lipoamidase activity | cholesterol + fatty acid | - |
? | |
3.1.1.13 | cholesteryl esters + H2O | Homo sapiens | important role in fat digestion in infants | cholesterol + fatty acid | - |
? | |
3.1.1.13 | cholesteryl esters + H2O | Rattus sp. | important role in fat digestion in infants | cholesterol + fatty acid | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.13 | Homo sapiens | - |
- |
- |
3.1.1.13 | Rattus sp. | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.13 | milk | - |
Homo sapiens | - |
3.1.1.13 | pancreas | - |
Rattus sp. | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.1.1.13 | 0.027 | - |
in absence of taurocholic acid | Homo sapiens |
3.1.1.13 | 0.045 | - |
in presence of 2 mM taurocholic acid | Homo sapiens |
3.1.1.13 | 0.066 | - |
in presence of 10 mM taurocholic acid | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.13 | cholesteryl esters + H2O | shows also lipoamidase activity | Homo sapiens | cholesterol + fatty acid | - |
? | |
3.1.1.13 | cholesteryl esters + H2O | shows also lipoamidase activity | Rattus sp. | cholesterol + fatty acid | - |
? | |
3.1.1.13 | cholesteryl esters + H2O | important role in fat digestion in infants | Homo sapiens | cholesterol + fatty acid | - |
? | |
3.1.1.13 | cholesteryl esters + H2O | important role in fat digestion in infants | Rattus sp. | cholesterol + fatty acid | - |
? | |
3.1.1.13 | lipoyl 4-aminobenzoate + H2O | - |
Homo sapiens | 4-aminobenzoate + lipoic acid | - |
? | |
3.1.1.13 | lipoyl 4-aminobenzoate + H2O | - |
Rattus sp. | 4-aminobenzoate + lipoic acid | - |
? | |
3.1.1.13 | p-nitrophenyl acetate + H2O | - |
Homo sapiens | p-nitrophenol + acetic acid | - |
? | |
3.1.1.13 | p-nitrophenyl acetate + H2O | - |
Rattus sp. | p-nitrophenol + acetic acid | - |
? | |
3.1.1.13 | triacetin + H2O | - |
Homo sapiens | ? + acetic acid | - |
? | |
3.1.1.13 | triacetin + H2O | - |
Rattus sp. | ? + acetic acid | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.1.13 | bile salt-activated lipase | - |
Homo sapiens |