Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Schirch, V.
    Purification of folate-dependent enzymes from rabbit liver (1997), Methods Enzymol., 281, 146-161.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.3.2 5-Formyltetrahydrohomofolate
-
 Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.3.3.2 0.0002
-
 5-formyl-tetrahydropteroyl-pentaglutamate
-
 Oryctolagus cuniculus
6.3.3.2 0.0003
-
 ATP
-
 Oryctolagus cuniculus
6.3.3.2 0.008
-
 5-formyltetrahydrofolate
-
 Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.3.2 Ca2+ can replace Mg2+ Oryctolagus cuniculus
6.3.3.2 Co2+ can replace Mg2+ Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
6.3.3.2 Oryctolagus cuniculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.3.2
-
 Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.3.2 liver
-
 Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.3.3.2 13
-
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.3.2 ATP + 5-formyltetrahydrofolate
-
 Oryctolagus cuniculus ADP + phosphate + 5,10-methylenetetrahydrofolate
-
 ?
6.3.3.2 ATP + 5-formyltetrahydrofolate ATP in form of MgATP2- Oryctolagus cuniculus ADP + phosphate + 5,10-methenyltetrahydrofolate
-
 ?
6.3.3.2 ATP + 5-formyltetrahydrohomofolate
-
 Oryctolagus cuniculus ?
-
 ?
6.3.3.2 ATP + 5-formyltetrahydropteroyl-pentaglutamate
-
 Oryctolagus cuniculus ?
-
 ?
6.3.3.2 CTP + 5-formyltetrahydrofolate as effective as ATP Oryctolagus cuniculus CDP + phosphate + 5,10-methylenetetrahydrofolate
-
 ?