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Literature summary extracted from

  • Gδde, G.
    A comparative study of octopine dehydrogenase isoenzymes in gastropod, bivalve and cephalopod molluscs (1980), Comp. Biochem. Physiol. B, 67, 575-582.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.1.11 octopine product inhibition Buccinum undatum
1.5.1.11 octopine product inhibition Mytilus edulis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.5.1.11 0.01
-
NADH foot muscle enzyme Buccinum undatum
1.5.1.11 0.011
-
NADH digestive gland enzyme Mytilus edulis
1.5.1.11 0.019
-
NADH digestive gland enzyme Buccinum undatum
1.5.1.11 0.021
-
NADH foot muscle enzyme Mytilus edulis
1.5.1.11 0.022
-
NAD+ NADH, adductor muscle enzyme Mytilus edulis
1.5.1.11 0.022
-
NAD+ adductor muscle enzyme Mytilus edulis
1.5.1.11 0.023
-
NAD+ digestive gland enzyme Mytilus edulis
1.5.1.11 0.025
-
NAD+ gill enzyme Mytilus edulis
1.5.1.11 0.036
-
NAD+ foot muscle enzyme Mytilus edulis
1.5.1.11 0.08
-
NADH NAD+, digestive gland enzyme Buccinum undatum
1.5.1.11 0.1
-
D-octopine NAD+, foot muscle enzyme Buccinum undatum
1.5.1.11 0.18
-
octopine digestive gland enzyme Buccinum undatum
1.5.1.11 0.22
-
octopine NADH, gill enzyme Mytilus edulis
1.5.1.11 0.27
-
octopine foot muscle enzyme Buccinum undatum
1.5.1.11 0.3
-
Arg digestive gland enzyme Mytilus edulis
1.5.1.11 0.4
-
pyruvate digestive gland enzyme Mytilus edulis
1.5.1.11 0.8
-
pyruvate pyruvate, foot muscle enzyme Mytilus edulis
1.5.1.11 0.85
-
octopine gill enzyme Mytilus edulis
1.5.1.11 0.9
-
Arg gill enzyme Mytilus edulis
1.5.1.11 1.1
-
Arg Arg, foot muscle enzyme Mytilus edulis
1.5.1.11 1.2
-
Arg pyruvate, gill enzyme Mytilus edulis
1.5.1.11 1.22
-
Arg digestive gland enzyme Buccinum undatum
1.5.1.11 1.3
-
octopine adductor muscle enzyme Mytilus edulis
1.5.1.11 1.3
-
octopine pyruvate, adductor muscle enzyme Mytilus edulis
1.5.1.11 1.35
-
Arg foot muscle enzyme Buccinum undatum
1.5.1.11 1.4
-
L-Arg octopine, foot muscle enzyme Mytilus edulis
1.5.1.11 1.56
-
pyruvate digestive gland enzyme Buccinum undatum
1.5.1.11 1.6
-
oxaloacetate pyruvate, foot muscle enzyme Buccinum undatum
1.5.1.11 1.7
-
octopine digestive gland enzyme Mytilus edulis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.11 additional information Mytilus edulis
-
?
-
?
1.5.1.11 additional information Loligo vulgaris octopine is produced in the mantle via the reaction of the muscle isoenzyme and is subsequently flushed out into the blood and transported to other tissues such as the optic lobe for re-oxidation via the optic lobe isoenzyme ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.11 Acanthocardia tuberculata
-
-
-
1.5.1.11 Buccinum undatum
-
-
-
1.5.1.11 Loligo vulgaris
-
-
-
1.5.1.11 Mytilus edulis
-
-
-
1.5.1.11 Pecten jacobaeus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.1.11 adductor
-
Mytilus edulis
-
1.5.1.11 adductor
-
Pecten jacobaeus
-
1.5.1.11 adductor
-
Acanthocardia tuberculata
-
1.5.1.11 digestive gland
-
Mytilus edulis
-
1.5.1.11 digestive gland
-
Pecten jacobaeus
-
1.5.1.11 digestive gland
-
Buccinum undatum
-
1.5.1.11 foot muscle
-
Mytilus edulis
-
1.5.1.11 foot muscle
-
Buccinum undatum
-
1.5.1.11 foot muscle
-
Acanthocardia tuberculata
-
1.5.1.11 gill
-
Mytilus edulis
-
1.5.1.11 gill
-
Pecten jacobaeus
-
1.5.1.11 gill
-
Buccinum undatum
-
1.5.1.11 mantle muscle
-
Loligo vulgaris
-
1.5.1.11 mantle muscle
-
Pecten jacobaeus
-
1.5.1.11 mantle tissue
-
Loligo vulgaris
-
1.5.1.11 optic lobe
-
Loligo vulgaris
-
1.5.1.11 optic lobe
-
Pecten jacobaeus
-
1.5.1.11 radular muscle
-
Buccinum undatum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.11 L-Arg + oxaloacetate + NADH
-
Buccinum undatum ?
-
?
1.5.1.11 L-Arg + pyruvate + NADH
-
Loligo vulgaris N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O
-
?
1.5.1.11 L-Arg + pyruvate + NADH
-
Pecten jacobaeus N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O
-
?
1.5.1.11 L-Arg + pyruvate + NADH
-
Acanthocardia tuberculata N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O
-
?
1.5.1.11 L-Arg + pyruvate + NADH r Mytilus edulis N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O
-
?
1.5.1.11 L-Arg + pyruvate + NADH r Buccinum undatum N2-(D-1-carboxyethyl)-L-Arg + NAD+ + H2O
-
?
1.5.1.11 additional information
-
Mytilus edulis ?
-
?
1.5.1.11 additional information octopine is produced in the mantle via the reaction of the muscle isoenzyme and is subsequently flushed out into the blood and transported to other tissues such as the optic lobe for re-oxidation via the optic lobe isoenzyme Loligo vulgaris ?
-
?

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.1.11 NADH
-
Loligo vulgaris
1.5.1.11 NADH
-
Mytilus edulis
1.5.1.11 NADH
-
Pecten jacobaeus
1.5.1.11 NADH
-
Buccinum undatum
1.5.1.11 NADH
-
Acanthocardia tuberculata