Literature summary extracted from
Tret'iakov, O; Ryzhova, T.A.; Velichutina, I.V.; Kostikova, T.R.; Miasnikov, A.N.; Smirnov, M.N.; Domkin, V.D.
Glycine amide ribonucleotide synthetase (EC 6.3.4.13) - is aminoimidazole ribonucleotide synthetase (EC 6.3.3.1) from Saccharomyces cerevisiae (1995), Biokhimiia, 60, 2011-2021.
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
6.3.3.1 |
AMP |
competitive to ATP |
Saccharomyces cerevisiae |
|
Metals/Ions
EC Number |
Metals/Ions |
Comment |
Organism |
Structure |
---|
6.3.3.1 |
K+ |
absolutely required |
Saccharomyces cerevisiae |
|
6.3.3.1 |
Mg2+ |
absolutely required |
Saccharomyces cerevisiae |
|
Molecular Weight [Da]
EC Number |
Molecular Weight [Da] |
Molecular Weight Maximum [Da] |
Comment |
Organism |
---|
6.3.3.1 |
87000 |
- |
2 * 87000, bifunctional enzyme with AIR synthetase activity and phosphoribosyl-glycinamide synthetase activity |
Saccharomyces cerevisiae |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
6.3.3.1 |
Saccharomyces cerevisiae |
- |
bifunctional enzyme with AIR synthetase activity and phosphoribosyl-glycinamide synthetase activity |
- |
Purification (Commentary)
EC Number |
Purification (Comment) |
Organism |
---|
6.3.3.1 |
bifunctional enzyme with AIR synthetase activity and phosphoribosyl-glycinamide synthetase activity |
Saccharomyces cerevisiae |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
6.3.3.1 |
ATP + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine |
- |
Saccharomyces cerevisiae |
ADP + phosphate + 1-(5-phosphoribosyl)-5-aminoimidazole |
- |
? |
|
Subunits
EC Number |
Subunits |
Comment |
Organism |
---|
6.3.3.1 |
dimer |
2 * 87000, bifunctional enzyme with AIR synthetase activity and phosphoribosyl-glycinamide synthetase activity |
Saccharomyces cerevisiae |