Literature summary extracted from

Michaud, C.; Blanot, D.; Flouret, B.; van Heijenoort, J.
Partial purification and specificity studies of the D-glutamate-adding and D-alanyl-D-alanine-adding enzymes from Escherichia coli K12 (1987), Eur. J. Biochem., 166, 631-637.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
6.3.2.9	1-phospho-N-acetylmuramoyl-L-Ala-D-Glu	-	Escherichia coli
6.3.2.9	D-2-Aminoadipic acid	-	Escherichia coli
6.3.2.9	D-Asp	weak	Escherichia coli
6.3.2.9	D-Gln	weak	Escherichia coli
6.3.2.9	D-pyroglutamic acid	-	Escherichia coli
6.3.2.9	dihydrouridine 5'-diphosphate-N-acetylmuramoyl-L-Ala-D-Glu	-	Escherichia coli
6.3.2.9	DL-2-Amino-4-phosphonobutyric acid	-	Escherichia coli
6.3.2.9	DL-2-aminopimelic acid	-	Escherichia coli
6.3.2.9	L-Glu	-	Escherichia coli
6.3.2.9	UDP-N-acetylmuramoyl-L-Ala-D-Glu	-	Escherichia coli

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
6.3.2.9	0.0055	-	UDP-N-acetylmuramoyl-L-Ala	-	Escherichia coli
6.3.2.9	0.01	-	dihydrouridine 5'-diphosphate-N-acetylmuramoyl-L-Ala	-	Escherichia coli
6.3.2.9	0.2	-	1-phospho-N-acetylmuramoyl-L-Ala	-	Escherichia coli
6.3.2.9	0.28	-	D-Glu	-	Escherichia coli

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
6.3.2.9	52000	-	gel filtration	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.3.2.9	Escherichia coli	-	K12	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.3.2.9	ATP + 1-phospho-N-acetylmuramoyl-L-Ala + Glu	-	Escherichia coli	ADP + phosphate + 1-phospho-N-acetylmuramoyl-L-Ala-D-Glu	-	?
6.3.2.9	ATP + dihydrouridine 5'-diphosphate-N-acetylmuramoyl-L-Ala + Glu	-	Escherichia coli	ADP + phosphate + dihydrouridine 5'-diphosphate-N-acetylmuramoyl-L-Ala-D-Glu	-	?
6.3.2.9	ATP + UDP-N-acetylmuramoyl-L-Ala + Glu	-	Escherichia coli	ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu	-	?

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Release 2023.1 (January 2023)