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Literature summary extracted from

  • Liger, D.; Blanot, D.; van Heijenoort, J.
    Effect of various alanine analogues on the L-alanine-adding enzyme from Escherichia coli (1991), FEMS Microbiol. Lett., 80, 111-116.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.8 3,3,3-Trifluoro-DL-Ala
-
 Escherichia coli
6.3.2.8 3,3-Difluoro-L-Ala
-
 Escherichia coli
6.3.2.8 3-chloro-L-Ala
-
 Escherichia coli
6.3.2.8 3-Cyano-L-Ala
-
 Escherichia coli
6.3.2.8 3-Fluoro-L-Ala
-
 Escherichia coli
6.3.2.8 Gly
-
 Escherichia coli
6.3.2.8 L-2-aminobutyrate
-
 Escherichia coli
6.3.2.8 L-Cys weak Escherichia coli
6.3.2.8 L-lactate
-
 Escherichia coli
6.3.2.8 L-propargylglycine
-
 Escherichia coli
6.3.2.8 L-Ser
-
 Escherichia coli
6.3.2.8 L-Vinylglycine
-
 Escherichia coli
6.3.2.8 N-Methyl-L-Ala weak Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.8 Escherichia coli
-
 K12HfrH
-
6.3.2.8 Escherichia coli K12HfrH
-
 K12HfrH
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.8 ATP + UDP-N-acetylmuramate + L-Ala
-
 Escherichia coli ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala
-
 ?
6.3.2.8 ATP + UDP-N-acetylmuramate + L-Ala
-
 Escherichia coli K12HfrH ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala
-
 ?