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Literature summary extracted from

  • Boll, M.; Albracht, S.S.P.; Fuchs, G.
    Benzoyl-CoA reductase (dearomatizing), a key enzyme of anaerobic aromatic metabolism. A study of adenosinetriphosphatase activity, ATP stoichiometry of the reaction and EPR properties of the enzyme (1997), Eur. J. Biochem., 244, 840-851.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.3.7.8 adenosine 5'-[beta,gamma-imido]triphosphate potent inhibitor Thauera aromatica
1.3.7.8 adenosine 5'-[beta,gamma-methylene]triphosphate inhibition only at high concentration, above 10 mM, in presence of 5 mM MgATP2- Thauera aromatica

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.7.8 ADP competitive with respect to ATP Thauera aromatica

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.7.8 0.015
-
 benzoyl-CoA
-
 Thauera aromatica
1.3.7.8 0.15
-
 NH2OH
-
 Thauera aromatica

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.3.7.8 Iron contains two separate [2Fe-2S]clusters and two interacting [4Fe-4S]clusters Thauera aromatica
1.3.7.8 Mg2+ MgATP2- is required for activity Thauera aromatica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.7.8 Benzoyl-CoA + reduced acceptor + ATP Thauera aromatica key enzyme of anaerobic aromatic metabolism ?
-
 ?
1.3.7.8 Benzoyl-CoA + reduced acceptor + ATP Thauera aromatica K172 key enzyme of anaerobic aromatic metabolism ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.7.8 Thauera aromatica
-
-
-
1.3.7.8 Thauera aromatica K172
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.7.8
-
 Thauera aromatica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.7.8 benzoyl-CoA + reduced acceptor + ATP
-
 Thauera aromatica cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + ADP + phosphate
-
 ir
1.3.7.8 benzoyl-CoA + reduced acceptor + ATP
-
 Thauera aromatica K172 cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + ADP + phosphate
-
 ir
1.3.7.8 Benzoyl-CoA + reduced acceptor + ATP key enzyme of anaerobic aromatic metabolism Thauera aromatica ?
-
 ?
1.3.7.8 Benzoyl-CoA + reduced acceptor + ATP key enzyme of anaerobic aromatic metabolism Thauera aromatica K172 ?
-
 ?
1.3.7.8 NH2OH + ATP + H2O
-
 Thauera aromatica ?
-
 ?
1.3.7.8 NH2OH + ATP + H2O
-
 Thauera aromatica K172 ?
-
 ?