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Literature summary extracted from
- The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain (1980), J. Biol. Chem., 255, 10896-10901.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.25 | NH4+ | stimulatory | Bos taurus |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.25 | Ca2+ | - |
Bos taurus | |
| 3.1.3.25 | F- | 50% inhibitory at 1 mM | Bos taurus | |
| 3.1.3.25 | Li+ | - |
Bos taurus | |
| 3.1.3.25 | Mn2+ | - |
Bos taurus | |
| 3.1.3.25 | SO42- | 40% inhibitory at 17 mM | Bos taurus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.3.25 | 0.1 | - |
L-myo-Inositol 1-phosphate | - |
Bos taurus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.25 | Ca2+ | 3% activation at 3.5 mM | Bos taurus | |
| 3.1.3.25 | Co2+ | 3% activation at 3.5 mM | Bos taurus | |
| 3.1.3.25 | Cu2+ | 3% activation at 3.5 mM | Bos taurus | |
| 3.1.3.25 | Fe2+ | 3% activation at 3.5 mM | Bos taurus | |
| 3.1.3.25 | K+ | - |
Bos taurus | |
| 3.1.3.25 | Mg2+ | completely dependent on | Bos taurus | |
| 3.1.3.25 | Mn2+ | 3% activation at 3.5 mM | Bos taurus | |
| 3.1.3.25 | Na+ | - |
Bos taurus | |
| 3.1.3.25 | NH4+ | stimulatory | Bos taurus | |
| 3.1.3.25 | Zn2+ | activation at 3.5 mM | Bos taurus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.3.25 | 58000 | - |
gel filtration | Bos taurus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.25 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.3.25 | partial | Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.3.25 | brain | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.25 | 2'-AMP + H2O | - |
Bos taurus | adenosine + phosphate | - |
? | |
| 3.1.3.25 | L-chiro-inositol-3-phosphate + H2O | - |
Bos taurus | ? | - |
? | |
| 3.1.3.25 | additional information | triphosphoinositide | Bos taurus | ? | - |
? | |
| 3.1.3.25 | myo-inositol 3-phosphate + H2O | - |
Bos taurus | myo-inositol + phosphate | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.3.25 | 7.5 | 8 | - |
Bos taurus |
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Release 2023.1 (January 2023)
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