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Literature summary extracted from

  • Talesa, V.; Romani, R.; Calvitti, M.; Rosi, G.; Giovannini, E.
    Acetylcholinesterase at high catalytic efficiency and substrate specificity in the optic lobe of Eledone moschata (Cephalopoda: Octopoda): biochemical characterization and histochemical localization (1998), Neurochem. Int., 33, 131-141.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.7 BW4c51
-
 Eledone moschata
3.1.1.7 diisopropylfluorophosphate
-
 Eledone moschata
3.1.1.7 edrophonium
-
 Eledone moschata
3.1.1.7 physostigmine
-
 Eledone moschata

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.7 0.11
-
 propionylthiocholine form II Eledone moschata
3.1.1.7 0.398
-
 propionylthiocholine form I Eledone moschata
3.1.1.7 0.72
-
 acetylthiocholine form II Eledone moschata

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.7 66000
-
 2 * 66000, SDS-PAGE Eledone moschata
3.1.1.7 135000 136000 gel filtration Eledone moschata

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.7 acetylcholine + H2O Eledone moschata
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Eledone moschata
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.7 forms I and II Eledone moschata

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.7 optic lobe
-
 Eledone moschata
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.7 700
-
-
 Eledone moschata

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.7 acetylcholine + H2O
-
 Eledone moschata choline + acetate
-
 ?
3.1.1.7 acetylcholine + H2O
-
 Eledone moschata ?
-
 ?
3.1.1.7 acetylthiocholine + H2O
-
 Eledone moschata thiocholine + acetate
-
 ?
3.1.1.7 butyrylthiocholine + H2O
-
 Eledone moschata butyrate + thiocholine
-
 ?
3.1.1.7 propionylthiocholine + H2O
-
 Eledone moschata propanoate + thiocholine
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.7 dimer 2 * 66000, SDS-PAGE Eledone moschata