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Literature summary extracted from

  • Guedes, R.N.C.; Zhu, K.Y.; Kambhampati, S.; Cover, B.A.
    Characterization of acetylcholinesterase purified from the lesser grain borer, Rhyzopertha dominica (Coleoptera: Bostrichidae) (1998), Comp. Biochem. Physiol. B, 119, 205-210.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.7 acetyl-[beta-methyl]thiocholine
-
 Rhyzopertha dominica
3.1.1.7 acetylthiocholine
-
 Rhyzopertha dominica
3.1.1.7 BW4c51
-
 Rhyzopertha dominica
3.1.1.7 ethopropazine partially Rhyzopertha dominica
3.1.1.7 physostigmine
-
 Rhyzopertha dominica
3.1.1.7 propionylthioacetylcholine
-
 Rhyzopertha dominica

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.7 56000
-
 2 * 56000, SDS-PAGE Rhyzopertha dominica
3.1.1.7 107000
-
 non-denaturing PAGE Rhyzopertha dominica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.7 acetylcholine + H2O Rhyzopertha dominica inactivation of transmitter substance operating in cholinergic neurotransmission ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Rhyzopertha dominica
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.7
-
 Rhyzopertha dominica

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.7 4.7
-
-
 Rhyzopertha dominica

Storage Stability

EC Number Storage Stability Organism
3.1.1.7 4°C, 20% glycerol, 3 days Rhyzopertha dominica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.7 acetyl-[beta-methyl]thiocholine + H2O
-
 Rhyzopertha dominica acetate + [beta-methyl]thiocholine
-
 ?
3.1.1.7 acetylcholine + H2O inactivation of transmitter substance operating in cholinergic neurotransmission Rhyzopertha dominica ?
-
 ?
3.1.1.7 acetylthiocholine + H2O
-
 Rhyzopertha dominica thiocholine + acetate
-
 ?
3.1.1.7 butyrylthiocholine + H2O
-
 Rhyzopertha dominica butyrate + thiocholine
-
 ?
3.1.1.7 propionylthiocholine + H2O
-
 Rhyzopertha dominica propanoate + thiocholine
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.7 dimer 2 * 56000, SDS-PAGE Rhyzopertha dominica