Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Miklankova, P.; Linster, E.; Boyer, J.B.; Weidenhausen, J.; Mueller, J.; Armbruster, L.; Lapouge, K.; De La Torre, C.; Bienvenut, W.; Sticht, C.; Mann, M.; Meinnel, T.; Sinning, I.; Giglione, C.; Hell, R.; Wirtz, M.
    HYPK promotes the activity of the Nalpha-acetyltransferase A complex to determine proteostasis of nonAc-X2/N-degron-containing proteins (2022), Sci. Adv., 8, eabn6153.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.255 Arabidopsis thaliana Q8VZM1 and Q9FKI4 auxiliary subunit NAA15, Q9FKI4i.e. catalytic subunit NAA10
-

Synonyms

EC Number Synonyms Comment Organism
2.3.1.255 AA15
-
 Arabidopsis thaliana
2.3.1.255 At1g80410
-
 Arabidopsis thaliana
2.3.1.255 At5g13780
-
 Arabidopsis thaliana
2.3.1.255 NAA10
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.3.1.255 physiological function Huntingtin yeast partner (HYPK) physically interacts with the ribosome-anchoring subunit of NatA and promotes Nalpha-terminal acetylation of diverse NatA substrates. Loss-of-HYPK mutants are remarkably resistant to drought stress and strongly resemble the phenotype of NatA-depleted plants. HYPK impairs plant metabolism and development, predominantly by regulating NatA activity Arabidopsis thaliana