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Literature summary extracted from

  • Fritsch, L.; Robin, P.; Mathieu, J.R.; Souidi, M.; Hinaux, H.; Rougeulle, C.; Harel-Bellan, A.; Ameyar-Zazoua, M.; Ait-Si-Ali, S.
    A subset of the histone H3 lysine 9 methyltransferases Suv39h1, G9a, GLP, and SETDB1 participate in a multimeric complex (2010), Mol. Cell, 37, 46-56.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.355 Homo sapiens O43463
-
-
2.1.1.366 Homo sapiens Q15047
-
-
2.1.1.367 Homo sapiens Q96KQ7
-
-
2.1.1.367 Homo sapiens Q9H9B1
-
-
2.1.1.368 Homo sapiens Q96KQ7
-
-
2.1.1.368 Homo sapiens Q9H9B1
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.355 HeLa cell
-
 Homo sapiens
-
2.1.1.366 HeLa cell
-
 Homo sapiens
-
2.1.1.367 HeLa cell
-
 Homo sapiens
-
2.1.1.368 HeLa cell
-
 Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
2.1.1.355 SUV39H1
-
 Homo sapiens
2.1.1.366 SETDB1
-
 Homo sapiens
2.1.1.367 EHMT1
-
 Homo sapiens
2.1.1.367 EHMT2
-
 Homo sapiens
2.1.1.367 G9a
-
 Homo sapiens
2.1.1.367 GLP
-
 Homo sapiens
2.1.1.367 KMT1C
-
 Homo sapiens
2.1.1.367 KMT1D
-
 Homo sapiens
2.1.1.368 EHMT1
-
 Homo sapiens
2.1.1.368 EHMT2
-
 Homo sapiens
2.1.1.368 G9a
-
 Homo sapiens
2.1.1.368 GLP
-
 Homo sapiens
2.1.1.368 KMT1C
-
 Homo sapiens
2.1.1.368 KMT1D
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
2.1.1.355 physiological function histone H3K9 methyltransferases G9a/KMT1C, GLP/KMT1D, SETDB1/KMT1E, and Suv39h1/KMT1A, coexist in the same megacomplex. In Suv39h or G9a null cells, the remaining histone H3K9 methyltransferases are destabilized at the protein level, indicating. The four enzymes are recruited to major satellite repeats, a known Suv39h1 genomic target, but also to multiple G9a target genes. The four H3K9 histone H3K9 methyltransferases display a functional cooperation in the regulation of known G9a target genes Homo sapiens
2.1.1.366 physiological function histone H3K9 methyltransferases G9a/KMT1C, GLP/KMT1D, SETDB1/KMT1E, and Suv39h1/KMT1A, coexist in the same megacomplex. In Suv39h or G9a null cells, the remaining histone H3K9 methyltransferases are destabilized at the protein level, indicating. The four enzymes are recruited to major satellite repeats, a known Suv39h1 genomic target, but also to multiple G9a target genes. The four H3K9 histone H3K9 methyltransferases display a functional cooperation in the regulation of known G9a target genes Homo sapiens
2.1.1.367 physiological function histone H3K9 methyltransferases G9a/KMT1C, GLP/KMT1D, SETDB1/KMT1E, and Suv39h1/KMT1A, coexist in the same megacomplex. In Suv39h or G9a null cells, the remaining histone H3K9 methyltransferases are destabilized at the protein level, indicating. The four enzymes are recruited to major satellite repeats, a known Suv39h1 genomic target, but also to multiple G9a target genes. The four H3K9 histone H3K9 methyltransferases display a functional cooperation in the regulation of known G9a target genes Homo sapiens
2.1.1.368 physiological function histone H3K9 methyltransferases G9a/KMT1C, GLP/KMT1D, SETDB1/KMT1E, and Suv39h1/KMT1A, coexist in the same megacomplex. In Suv39h or G9a null cells, the remaining histone H3K9 methyltransferases are destabilized at the protein level, indicating. The four enzymes are recruited to major satellite repeats, a known Suv39h1 genomic target, but also to multiple G9a target genes. The four H3K9 histone H3K9 methyltransferases display a functional cooperation in the regulation of known G9a target genes Homo sapiens