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Literature summary extracted from
- The H3K9 methylation writer SETDB1 and its reader MPP8 cooperate to silence satellite DNA repeats in mouse embryonic stem cells (2019), Genes (Basel), 10, 750 .
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.1.1.366 | Mus musculus | - |
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- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.1.1.366 | embryonic stem cell | - |
Mus musculus | - |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 2.1.1.366 | physiological function | H3K9 methylation reader M-phase phosphoprotein 8 (MPP8) interacts physically and functionally with SETDB1 in embryonic stem cells. MPP8 and SETDB1 coregulate a significant number of common genomic targets, especially the DNA satellite repeats | Mus musculus |
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